The passenger compartment of the Clio remained stable in the frontal offset test. Protection of all critical body areas was good for the passenger dummy. Dummy readings showed good protection for the knees and femurs of both the driver and passenger. Renault demonstrated that a similar level of protection would be provided to occupants of different sizes and to those sitting in different positions. In the full-width rigid barrier test, protection was good or adequate for all critical body areas of the driver and rear passenger. Maximum points were scored in the side barrier test, all critical parts of the body being well protected. Even in the more severe side pole impact, protection of the chest was adequate and that of other body regions was good. In the Tests on the front seats and head restraints demonstrated good protection against whiplash injuries in the event of a rear-end collision. The standard-fit autonomous emergency braking (AEB) system performed well in tests of its functionality at the low speeds, typical of city driving, at which many whiplash injuries occur.

In both the frontal offset and the side barrier tests, protection of the 6 and 10 year children was good or adequate. The front passenger airbag can be disabled to allow a rearward-facing child restraint to be used in that seating position. Clear information is provided to the driver regarding the status of the airbag and the system was rewarded. All of the restraint types for which the Clio is designed could be properly installed and accommodated.

The bonnet provided predominantly good or adequate protection to the head of a struck pedestrian over most of its surface, with some poor results recorded on the stiff windscreen pillars. Protection of the pelvis was good in places but weak and poor results were also recorded. Similarly, the protection offered to pedestrians' legs was weak at the outer edges but good elsewhere. The AEB system can detect vulnerable road users like pedestrians and cyclists, as well as other vehicles, and performed well in tests of both these functionalities.

The AEB system performed well in tests of its functionality at highway speeds. The speed assistance system uses a camera to recognise the local speed limit and offers the driver the opportunity to set the limiter appropriately. The lane support system helps to prevent inadvertent drifting out of lane but does not intervene in more critical scenarios, as the systems of some cars do. There is a seatbelt reminder for the front and rear seats.