The passenger compartment remained stable in the frontal offset test.  With the exception of the driver's right tibia, which rated as marginal, protection of both adult dummies was good, including the knees and femurs.  Renault showed that a similar level of protection would be provided to occupants of different sizes and to those sat in different positions.  In the full-width rigid barrier test, protection of the head and chest of the rear passenger was rated as marginal and that of all other critical body areas was good or adequate.  In both the side barrier test and the more severe side pole impact, protection was good and the Koleos scored maximum points in these tests.  Tests on the front seats and head restraints demonstrated good protection against whiplash injuries in the event of a rear-end collision.  A geometric assessment of the rear seats also indicated good whiplash protection.  The Koleos has, as standard, an autonomous emergency braking system.  Tests of this system's functionality at the low speeds at which many whiplash injuries are caused showed good performance.

In the frontal offset test, readings of tension in the neck of the 10 year dummy indicated poor protection for this body area.  Protection of the chest of the 6 year dummy was weak, based on decelerations measured by the dummy.  Otherwise, protection of the child dummies was good or adequate.  In the side barrier test, protection of both dummies was good for all critical parts of the body.  The front passenger airbag can be disabled to allow a rearward-facing child restraint to be used in that seating position.  Clear information is provided to the driver regarding the status of the airbag and the system was rewarded.  All of the restraint types for which the Koleos is designed could be properly installed and accommodated in the car.

The protection provided by the bonnet surface to the head of a struck pedestrian was predominantly good or adequate, with poor results recorded on the stiff windscreen pillars.  The bumper gave good or adequate protection to pedestrians' legs but protection of the pelvis was mixed, with good and poor results.  The autonomous emergency braking system is not designed to react to pedestrians.

The Koleos has a seatbelt reminder as standard for the front and rear seats.  The speed assistance system identifies the local speed limit and allows the driver to set the limiter appropriately.  A lane departure warning system is standard.  The autonomous emergency braking system performed adequately in tests of its functionality at highway speeds.