The passenger compartment of the Cherokee remained stable in the frontal offset test. Dummy readings indicated good protection of the knees and femurs of both driver and passenger. Jeep showed that a similar level of protection would be provided to occupants of different sizes and to those sitting in different positions. In the full-width rigid barrier test, protection of all critical body areas was good or adequate for both the driver and the rear seat passenger. In the side barrier impact, the Cherokee scored maximum points with good protection of all critical parts of the body. In the more severe side pole test, dummy readings of rib compression indicated marginal protection of the chest.Tests on the front seats and head restraints demonstrated marginal protection against whiplash injuries in the event of a rear-end collision. A geometric assessment of the rear seats also indicated marginal whiplash protection. The Cherokee has, as standard, an autonomous emergency braking (AEB) system which operates at the low speeds, typical of city driving, at which many whiplash injuries occur. Tests of this functionality showed poor performance, the system failing to mitigate collisions at speeds below 20km/h in some scenarios. In any case, the car was not eligible for points for this technology owing to the marginal rating for its dynamic whiplash performance.

In the frontal offset test, dummy readings of neck tension in the 10-year dummy indicated weak protection. Protection of other critical body areas was good or adequate for both dummies. In the side barrier test, protection was good all-round. The front passenger airbag cannot be disabled so rearward-facing child restraints should not be used in this seating position. All restraint types for which the Cherokee is designed could be properly installed and accommodated in the car.

The bonnet provided good or adequate protection at nearly all points on the bonnet surface, with some poor results recorded at the base of the windscreen and on the stiff windscreen pillars. The bumper provided good protection to pedestrians' legs but protection of the pelvis was mixed, with areas of good and poor protection. The AEB system responds to some vulnerable road users, as well as to other vehicles. In tests of its response to pedestrians, the system showed marginal performance, with collisions avoided or mitigated only in some scenarios. The system does not respond to faster-moving road-users like cyclists.

In tests of its response to other cars at highway speeds, the AEB system demonstrated adequate performance. A seatbelt reminder is standard for the front and rear seats. A lane support system helps to prevent inadvertent drifting out of lane and also intervenes more aggressively in some critical situations. A driver-set speed limiter helps to prevent over-speeding, and is fitted as standard across the range.