The Škoda Kamiq is structurally identical to the Škoda Scala rated earlier in 2019 by Euro NCAP, and has the same fitment of safety equipment.  Some additional tests have been conducted where small differences might occur owing to the different ride-heights.  Accordingly, this assessment is based on that of the Scala and the results of the additional tests.

The passenger compartment of the Kamiq remained stable in the frontal offset test. Dummy readings indicated good protection of the knees and femurs of the driver and passenger. Škoda showed that a similar level of protection would be provided to occupants of different sizes and to those sitting in different positions. In the full-width rigid barrier test, protection of all critical body areas was good or adequate for both the driver and rear passenger. In both the side barrier and the more severe side pole tests, protection of all critical body areas was good and the car scored full points in both of these tests. Tests on the front seats and head restraints demonstrated good protection against whiplash injuries in the event of a rear-end collision. A geometric assessment of the rear seats also indicated good whiplash protection. The standard-fit autonomous emergency braking (AEB) system performed well in tests of its functionality at the low speeds at which many whiplash injuries occur.

In the frontal test, protection of all critical body areas was good or adequate for both dummies, apart from the neck of the 10 year dummy, protection of which was rated as marginal, based on dummy readings of neck tension . In the side barrier impact, all critical body areas were well protected for both dummies and the Kamiq scored maximum points in this part of the assessment. The front passenger airbag can be disabled to allow a rearward-facing child restraint to be used in that seating position. Clear information is provided to the driver regarding the status of the airbag and the system was rewarded. All of the restraint types for which the Kamiq is designed could be properly installed and accommodated in the car.

The bonnet provided predominantly good or adequate protection to the head of a struck pedestrian, with some poor results recorded on the stiff windscreen pillars. The bumper provided good protection to pedestrians' legs and protection of the pelvis was also generally good. The Kamiq's AEB system can detect vulnerable road users like pedestrians and cyclists, as well as other vehicles. In tests, the system's response to both was good, with collisions avoided or mitigated in most cases.

The Kamiq has a seatbelt reminder system for the front and rear seats. The AEB system performed well in tests of its response to other vehicles at highway speeds. A driver-set speed limiter helps the driver not to over-speed while a lane support system helps prevent inadvertent drifting out of lane, as well as intervening more aggressively in some critical situations.